Denamarin Tablets 225mg for Medium Dogs



What is Denamarin?

The PAW Denamarin formula for dogs and cats combines the benefits of S-Adenosylmethionine (SAMe) and Silybin in one tablet when maximum liver support is needed.

S-Adenosylmethionine (SAMe) in Denamarin has been shown to increase levels of the antioxidant glutathione, which is an important compound which assists in the efficient functioning of the liver and provides protection of this important organ against toxins. Although SAMe is naturally produced by the liver, its production is decreased when the liver is compromised, leading to suboptimal levels of glutathione.

Silybin (derived from milk thistle) supports oxidative balance and helps the flow of bile through the liver. Bile is important in aiding digestion and nutrient absorption. Silybin may also support levels of glutathione which is an important compound protecting liver health. The silybin found in Denamarin is complexed with phosphatidylcholine, which has been shown to increase absorption compared to standardised milk thistle extracts.

Always read the label. Use only as directed.

  • The specific silybin used in Denamarin has been shown to provide better bioavailability in dogs and cats compared to the standardised milk thistle commonly available in health food stores and over-the-counter in pharmacies.
  • Provides comprehensive liver support with two active ingredients SAMe and Silybin.
  • May protect against negative effects on the liver caused by some medications.
  • May enhance levels of glutathione for better detoxification.
  • Silybin A+B acts as an antioxidant, helping protect against reactive oxygen compounds.
  • Very high safety profile.

Why use Denamarin?

Denamarin provides enhanced support to aid in liver detoxification mechanisms for liver disease or dysfunction such as the following:

  • Chronic hepatitis
  • Hepatic lipidosis
  • Cholangiohepatitis
  • Paracetamol toxicity
  • Corticosteroid use (Note: does not prevent corticosteroid induced hepatic vacuolar change)
  • Other acute or chronic hepatopathies, including hepatotoxins and neoplasia.

When the liver function is compromised, the exact cause can often be difficult to determine. Supporting the liver, regardless of the cause, is essential if function is to be improved.

How is Denmarin Administered?

Absorption of Denamarin is decreased when it is given with a meal.

For optimal absorption, administer Denamarin at least one hour before feeding your pet. For owners who find it difficult to administer tablets to their pets, Denamarin tablet(s) may be disguised in a small bite of moist food. It is not necessary to withhold water from your pet when giving Denamarin.

In cats, tablets or capsules can “stick” in the throat instead of passing into the stomach. Therefore, cat owners should gently administer a small amount of water (ask your veterinarian for details) immediately following tablet administration to aid swallowing.

Denamarin tablets should not be broken as the enteric coating of the Denamarin tablet protects the active ingredient from destruction while in the stomach. The number of tablets can be gradually reduced or increased at any time depending on the pet’s needs. When increasing or decreasing the dose, adjustments should be done in full tablet increments.

Many pets are maintained long-term on every-other-day or every-third-day administration.

Denamarin 90mg for cats & small dogs <5.9kg: 1 tablet
Denamarin 225mg for medium dogs 6-15.9kg: 1 tablet
Denamarin 425mg for large dogs:
16-29.9kg: 1 tablet
30-54.9kg: 2 tablets
>55kg: 3 tablets

Active Ingredients:

Contains S-Adenosylmethionine and Silybin Phosphatidylcholine Complex

Similar Products:

Denosyl Tablets is another great product by PAW Blackmores which works wonders for liver issues in dogs and cats. Denosyl Tablets contains S-Adenosylmethionine (SAMe) whereas Denmarin contains S-Adenosylmethionine (SAMe) and sylibin. The additional ingredient, sylibin used in Denamarin has been shown to provide better bioavailability in dogs and cats and works in conjunction with SAMe to promote healthy liver function.

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